Queen Adad-Guppi was the daughter of King Ashurbanipal and Ashursharrat l… and mother to King Nabonidus. It’s been suggested that she acted as a regent for Nabonidus when he abandoned Babylon in 552 BC for Tema. The Tema Stele (c. 6 century BC), represent an important part of the history of Tema and of the history of the Arabian Peninsula.
Queen Jezebel married King Ahab (r. 874-853 BC), of Samaria, the northern kingdom of Israel. Her daughter, Athaliah, was queen of Judah (r. 841–835 BC) and the only female monarch to sit on David’s throne in biblical history.
Queen Artemisia I was of Carian-Greek ethnicity by her father Lygdamis I (r. 520-484 BC), and half-Cretan by her mother. She took the throne after the death of her husband.
Sources state that Sagburu, Oracle of Nuska, aided King Enmerkar of Uruk (c. 3100 BC), to defeat his arch-nemesis, the king of Aratta, in Enmerkar and Ensukesdana.
Šērūʾa-ēṭirat was the eldest daughter of Assyrian King Esarhaddon (r. 681-669 BC) and the older sister of twins, Ashurbanipal and Šamaš-šuma-ukin, crown princes of Assyria and of Babylonia. She was likely involved in politics.