Enheduanna was the daughter of Sargon of Akkad, and composed 42 temple hymns and three stand-alone poems that are considered an important part of Mesopotamia's literary legacy.
Madaki Hasa Askia* (c. 1500–1600) was the Daughter of Emperor Askia Muhammad I (Askia the Great), the first ruler of the Askia dynasty of the Songhai Empire. She became the first female Sultan of Kano.
Queen Khentkaus I lived during the Fourth Dynasty and may have been a daughter of Menkaure, inheriting the throne from her husband and half brother King Shepseskaf. She was obviously a very important figure, but little is known of her.
Queen Puabi ruled the Mesopotamian city-state of Ur around 2500 B.C. She died around 4,500 years ago, during the First Dynasty of Ur. Inscriptions on the cylinder seal found in her tomb do not mention her husband, suggesting that she ruled in her own right.