Tomyris was a queen of the Massagetae (c. 530 BC). After she found out about the death of her son, Spargapises, at the hands of Cyrus the Great she led the Massagetean army into war, and, during the battle defeated the Persians and destroyed most of their army.
Queen Jezebel married King Ahab (r. 874-853 BC), of Samaria, the northern kingdom of Israel. Her daughter, Athaliah, was queen of Judah (r. 841–835 BC) and the only female monarch to sit on David’s throne in biblical history.
Queen Artemisia I was of Carian-Greek ethnicity by her father Lygdamis I (r. 520-484 BC), and half-Cretan by her mother. She took the throne after the death of her husband.
Sources state that Sagburu, Oracle of Nuska, aided King Enmerkar of Uruk (c. 3100 BC), to defeat his arch-nemesis, the king of Aratta, in Enmerkar and Ensukesdana.